ID   A0N8V2_SHEEP            Unreviewed;       138 AA.
AC   A0N8V2;
DT   12-DEC-2006, integrated into UniProtKB/TrEMBL.
DT   12-DEC-2006, sequence version 1.
DT   11-DEC-2019, entry version 59.
DE   SubName: Full=Insuline-like growth factor-I (2) {ECO:0000313|EMBL:CAA35098.1};
GN   Name=IGF-I {ECO:0000313|EMBL:CAA35098.1};
OS   Ovis aries (Sheep).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Caprinae; Ovis.
OX   NCBI_TaxID=9940 {ECO:0000313|EMBL:CAA35098.1};
RN   [1] {ECO:0000313|EMBL:CAA35098.1}
RP   NUCLEOTIDE SEQUENCE.
RX   PubMed=2015053;
RA   Dickson M.C., Saunders J.C., Gilmour R.S.;
RT   "The ovine insulin-like growth factor-I gene: characterization, expression
RT   and identification of a putative promoter.";
RL   J. Mol. Endocrinol. 6:17-31(1991).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000256|RuleBase:RU000406,
CC       ECO:0000256|SAAS:SAAS00822014}.
CC   -!- SIMILARITY: Belongs to the insulin family.
CC       {ECO:0000256|RuleBase:RU000406, ECO:0000256|SAAS:SAAS00542063}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X17229; CAA35098.1; -; Genomic_DNA.
DR   EMBL; X51357; CAA35098.1; JOINED; Genomic_DNA.
DR   EMBL; X51358; CAA35098.1; JOINED; Genomic_DNA.
DR   EMBL; X51403; CAA35098.1; JOINED; Genomic_DNA.
DR   PIR; S22878; S22878.
DR   SMR; A0N8V2; -.
DR   GO; GO:0005615; C:extracellular space; IEA:InterPro.
DR   GO; GO:0008083; F:growth factor activity; IEA:InterPro.
DR   GO; GO:0005179; F:hormone activity; IEA:InterPro.
DR   InterPro; IPR022341; IGF-I.
DR   InterPro; IPR016179; Insulin-like.
DR   InterPro; IPR022350; Insulin-like_growth_factor.
DR   InterPro; IPR036438; Insulin-like_sf.
DR   InterPro; IPR022353; Insulin_CS.
DR   InterPro; IPR022352; Insulin_family.
DR   Pfam; PF00049; Insulin; 2.
DR   PRINTS; PR02002; INSLNLIKEGF.
DR   PRINTS; PR02005; INSLNLIKEGF1.
DR   PRINTS; PR00276; INSULINFAMLY.
DR   SMART; SM00078; IlGF; 1.
DR   SUPFAM; SSF56994; SSF56994; 1.
DR   PROSITE; PS00262; INSULIN; 1.
PE   3: Inferred from homology;
KW   Secreted {ECO:0000256|RuleBase:RU000406, ECO:0000256|SAAS:SAAS00822033};
KW   Signal {ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..33
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           34..138
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5002627671"
FT   DOMAIN          36..94
FT                   /note="IlGF"
FT                   /evidence="ECO:0000259|SMART:SM00078"
FT   REGION          110..138
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        124..138
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   138 AA;  15177 MW;  CF2026189A7980C1 CRC64;
     MVTPTQVKMP VTSSSHLFYL ALCLLAFTTS ATAGPETLCG AELVDALQFV CGDRGFYFNK
     PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKAA KSARSVRAQR HTDMPKAQKE
     VHLKNTSRGS AGNKNYRM
//