To reproduce the issue:
- Open COI.aln
- Open human_T1.fa
- Drag the sequence to the alignment
- Make the sequence reference
- Change the highlighting mode to "Disagreements"
- Use the dots
- Drag the reference sequence in the list of sequences
Expected result: the highlighting mode is the same, human_T1 is still the reference.
Actual result: human_T1 is not highlighted as reference anymore, the highlighting mode is not applied (however, it is still selected on the Options Panel)